The first step is the formation of the enolate. Journal of Materials Chemistry C 2017, 5 (19) , 4670-4676. The Michael reaction is also used in tandem with other re-actions.

Perhaps the best known of these is the Robinson an-nulation where the Michael addition occurs as the first step.

... Michael Reaction - Duration: 6:21. Summary. This sequence of Michael addition followed by intramolecular Aldol condensation proved extremely important early on in Enolates tend to react with α,β-unsaturated ketones via conjugate addition. 6:21. Adapted from reference 1.2d.
J. Org.Chem. DOI: 10.1039/C7TC00640C. More enolate stuff with the Michael Addition. However, despite myriad potential synthetic applications, there has not been any exclusive reviews of the thia‐Michael addition reaction. Reagents : commonly bases such as NaOH or KOH. with a myriad of substrates under radical (alkyne, alkene), base (Michael, isocyanate), and nucleophile (epoxide, halide) regimes. AK LECTURES 11,237 views. Application of DBU, blocked with phenyl glyoxylic acid as latent catalyst for the Michael addition reaction, results in a potlife of more than 10 days at 50°C, whereas the cure speed of the coating after deblocking with UV light and the film properties are completely comparable with those of the same binder catalysed with DBU as such. Michael Addition Polymerization (Conjugated Additon Reactions) The Michael addition reaction, also known as a conjugated addition, is a versatile method for the addition of various nucleophiles to (conjugated) unsaturated compounds with electron withdrawing substituents.This reaction was first discovered by Arthur Michael in 1887.

Many asymmetric variants exist.. The reaction is named after American chemist Arthur Michael (1853-1942). Look out for tautomerization! Examples of Michael Additions

The Michael Addition reaction Reaction type : Conjugate addition. reactions for the preparation of organic target products in synthetic organic chemistry The important of Michael addition So I choose the topic that (a) Berner, O. M.; Tedeschi, L.; Enders , D. Eur.
The Michael reaction or Michael addition is the nucleophilic addition of a carbanion or another nucleophile to an α,β-unsaturated carbonyl compound containing an electron withdrawing group.It belongs to the larger class of conjugate additions.This is one of the most useful methods for the mild formation of C–C bonds. Water-soluble luminescent hybrid aminoclay grafted with lanthanide complexes synthesized by a Michael-like addition reaction and its gas sensing application in PVP nanofiber. Therefore, this Focus Review plots the journey of the thia‐Michael addition reaction in organic synthesis, and is categorized according to catalyzed and catalyst‐free thia‐Michael addition reactions. The Michael addition is an organic reaction used to convert an activated methylene and a conjugated olefin to the corresponding addition product using a base catalyst followed by an acid work-up. Herein, the concepts and mechanisms of Michael addition reaction were discussed, and the applications of Michael addition reaction in the synthesis of natural products and …

Enolates undergo 1,4 addition to α, β-unsaturated carbonyl compounds is a process called a Michael addition. Scheme 1.2: The thiol-Michael reaction occurs between a thiol (blue) and an α, β-unsaturated carbonyl (red) in a 1,4-conjugate addition fashion to afford the corresponding